Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2024-11-10
Based on 398 first isolates · GER · Cystitis (lower UTI) · 2023-11-12 → 2024-11-10
Geriatrics
Per-organism detail: GER urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 85 % (81 %–88 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (6 %), Klebsiella pneumoniae (5 %), Pseudomonas aeruginosa (4 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
85 %
67 %
n = 30
meropenem MEM
trend · Escherichia coli reserve
84 %
87 %
n = 30
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
70 %
n = 30
ciprofloxacin CIP
trend · Escherichia coli
78 %
77 %
n = 30
ceftriaxone CRO
trend · Escherichia coli
77 %
63 %
n = 30
mecillinam MEC
trend · Escherichia coli lower UTI only
76 %
70 %
n = 30
74 %
63 %
n = 30
trimethoprim TMP
trend · Escherichia coli lower UTI only
67 %
80 %
n = 30
50 %
40 %
n = 30
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
14 %
13 %
n = 30
4 %
10 %
n = 30
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
4 %
7 %
n = 30

Most likely organisms for this profile

Escherichia coli
61 %
Enterococcus faecalis
10 %
Klebsiella pneumoniae
9 %
Proteus mirabilis
6 %
Pseudomonas aeruginosa
4 %
Staphylococcus aureus
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.