Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2024-11-10
Based on 613 first isolates · SURG · Skin / wound infection · 2023-11-12 → 2024-11-10
Surgery
Per-organism detail: SURG wound resistance view →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 52 % (48 %–56 %)
Best two-drug combination: vancomycin + meropenem covers 99 % (98 %–99 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Pseudomonas aeruginosa (16 %), Escherichia coli (13 %), Proteus mirabilis (8 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
52 %
58 %
n = 52
meropenem MEM
trend · Pseudomonas aeruginosa reserve
47 %
42 %
n = 52
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
44 %
42 %
n = 52
43 %
42 %
n = 52
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
40 %
46 %
n = 52
ceftriaxone CRO
trend · Escherichia coli
29 %
23 %
n = 52
27 %
19 %
n = 52
23 %
19 %
n = 52
15 %
19 %
n = 52
mecillinam MEC
not for this site
0 %
0 %
n = 52
trimethoprim TMP
not for this site
0 %
0 %
n = 52
nitrofurantoin NIT
not for this site
0 %
0 %
n = 52

Most likely organisms for this profile

Staphylococcus aureus
43 %
Pseudomonas aeruginosa
16 %
Escherichia coli
13 %
Enterococcus faecalis
9 %
Proteus mirabilis
8 %
Citrobacter freundii
6 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.