Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2024-11-17
Based on 395 first isolates · GER · Febrile UTI / pyelonephritis · 2023-11-19 → 2024-11-17
Geriatrics
Per-organism detail: GER urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
meropenem 84 % (80 %–87 %)
Carbapenem: reserve for ESBL / critically ill patients.
Not covered: Enterococcus faecalis (10 %), Staphylococcus aureus (4 %), Staphylococcus saprophyticus (2 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
nitrofurantoin NIT
trend · Escherichia coli not for this site
85 %
68 %
n = 34
meropenem MEM
trend · Escherichia coli reserve
84 %
88 %
n = 34
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
76 %
n = 34
ciprofloxacin CIP
trend · Escherichia coli
77 %
79 %
n = 34
ceftriaxone CRO
trend · Escherichia coli
77 %
68 %
n = 34
mecillinam MEC
trend · Escherichia coli not for this site
75 %
74 %
n = 34
73 %
65 %
n = 34
trimethoprim TMP
trend · Escherichia coli not for this site
68 %
85 %
n = 34
50 %
38 %
n = 34
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
14 %
9 %
n = 34
4 %
9 %
n = 34
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
4 %
6 %
n = 34

Most likely organisms for this profile

Escherichia coli
60 %
Enterococcus faecalis
10 %
Klebsiella pneumoniae
8 %
Proteus mirabilis
7 %
Pseudomonas aeruginosa
4 %
Staphylococcus aureus
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.