Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2024-11-24
Based on 398 first isolates · MED-B · Cystitis (lower UTI) · 2023-11-26 → 2024-11-24
Internal medicine B
Per-organism detail: MED-B urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 81 % (77 %–84 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (7 %), Klebsiella pneumoniae (6 %), Pseudomonas aeruginosa (5 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
85 %
82 %
n = 33
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
81 %
82 %
n = 33
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
82 %
n = 33
ceftriaxone CRO
trend · Escherichia coli
79 %
73 %
n = 33
mecillinam MEC
trend · Escherichia coli lower UTI only
79 %
76 %
n = 33
ciprofloxacin CIP
trend · Escherichia coli
76 %
73 %
n = 33
74 %
73 %
n = 33
trimethoprim TMP
trend · Escherichia coli lower UTI only
71 %
73 %
n = 33
49 %
48 %
n = 33
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
15 %
n = 33
4 %
3 %
n = 33
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
0 %
n = 33

Most likely organisms for this profile

Escherichia coli
54 %
Klebsiella pneumoniae
12 %
Enterococcus faecalis
10 %
Proteus mirabilis
7 %
Klebsiella oxytoca
5 %
Pseudomonas aeruginosa
5 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.