Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-01-05
Based on 1107 first isolates · ED · Febrile UTI / pyelonephritis · 2024-01-07 → 2025-01-05
Emergency department
Per-organism detail: ED urine resistance view → ⚠ 1 active alert in ED: they are taken into account below. View alerts →
Narrowest option reaching 80 % coverage, no active warning
ciprofloxacin 81 % (78 %–83 %)
Not covered: Enterococcus faecalis (8 %), Escherichia coli (4 %), Staphylococcus aureus (3 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
⚠ CPE case in the ward: carbapenem resistance possible
86 %
87 %
n = 90
nitrofurantoin NIT
trend · Escherichia coli not for this site
85 %
86 %
n = 90
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
82 %
84 %
n = 90
ciprofloxacin CIP
trend · Escherichia coli
81 %
81 %
n = 90
mecillinam MEC
trend · Escherichia coli not for this site
79 %
80 %
n = 90
ceftriaxone CRO
trend · Escherichia coli
79 %
77 %
n = 90
trimethoprim TMP
trend · Escherichia coli not for this site
76 %
76 %
n = 90
74 %
76 %
n = 90
51 %
46 %
n = 90
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
11 %
9 %
n = 90
4 %
4 %
n = 90
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
3 %
n = 90

Most likely organisms for this profile

Escherichia coli
56 %
Klebsiella pneumoniae
12 %
Enterococcus faecalis
8 %
Proteus mirabilis
7 %
Pseudomonas aeruginosa
4 %
Klebsiella oxytoca
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.