Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-01-05
Based on 392 first isolates · MED-B · Febrile UTI / pyelonephritis · 2024-01-07 → 2025-01-05
Internal medicine B
Per-organism detail: MED-B urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
meropenem 85 % (81 %–88 %)
Carbapenem: reserve for ESBL / critically ill patients.
Not covered: Enterococcus faecalis (10 %), Staphylococcus saprophyticus (3 %), Staphylococcus aureus (2 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
85 %
94 %
n = 32
nitrofurantoin NIT
trend · Escherichia coli not for this site
80 %
84 %
n = 32
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
91 %
n = 32
ceftriaxone CRO
trend · Escherichia coli
78 %
84 %
n = 32
mecillinam MEC
trend · Escherichia coli not for this site
78 %
81 %
n = 32
ciprofloxacin CIP
trend · Escherichia coli
75 %
88 %
n = 32
73 %
78 %
n = 32
trimethoprim TMP
trend · Escherichia coli not for this site
69 %
72 %
n = 32
49 %
41 %
n = 32
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
3 %
n = 32
4 %
6 %
n = 32
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
2 %
0 %
n = 32

Most likely organisms for this profile

Escherichia coli
54 %
Klebsiella pneumoniae
10 %
Enterococcus faecalis
10 %
Proteus mirabilis
7 %
Klebsiella oxytoca
5 %
Pseudomonas aeruginosa
5 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.