Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 318 first isolates · ED · Skin / wound infection · 2024-01-07 → 2025-01-05
Emergency department
Per-organism detail: ED wound resistance view → ⚠ 1 active alert in ED: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 53 % (48 %–59 %)
Best two-drug combination: ciprofloxacin + vancomycin covers 97 % (94 %–98 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Pseudomonas aeruginosa (14 %), Escherichia coli (14 %), Proteus mirabilis (8 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
53 %
60 %
n = 30
meropenem MEM
trend · Pseudomonas aeruginosa reserve
⚠ CPE case in the ward: carbapenem resistance possible
46 %
37 %
n = 30
43 %
33 %
n = 30
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
43 %
40 %
n = 30
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
42 %
53 %
n = 30
ceftriaxone CRO
trend · Escherichia coli
30 %
30 %
n = 30
27 %
27 %
n = 30
25 %
23 %
n = 30
14 %
10 %
n = 30
mecillinam MEC
not for this site
0 %
0 %
n = 30
trimethoprim TMP
not for this site
0 %
0 %
n = 30
nitrofurantoin NIT
not for this site
0 %
0 %
n = 30

Most likely organisms for this profile

Staphylococcus aureus
44 %
Pseudomonas aeruginosa
14 %
Escherichia coli
14 %
Enterococcus faecalis
9 %
Proteus mirabilis
8 %
Citrobacter freundii
5 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.