Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 305 first isolates · ED · Skin / wound infection · 2024-01-28 → 2025-01-26
Emergency department
Per-organism detail: ED wound resistance view → ⚠ 1 active alert in ED: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 54 % (48 %–59 %)
Best two-drug combination: ciprofloxacin + vancomycin covers 97 % (94 %–98 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Escherichia coli (14 %), Pseudomonas aeruginosa (14 %), Proteus mirabilis (8 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
54 %
68 %
n = 22
meropenem MEM
trend · Escherichia coli reserve
⚠ CPE case in the ward: carbapenem resistance possible
45 %
27 %
n = 22
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
43 %
59 %
n = 22
ciprofloxacin CIP
trend · Escherichia coli
43 %
32 %
n = 22
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
43 %
32 %
n = 22
ceftriaxone CRO
trend · Escherichia coli
30 %
27 %
n = 22
28 %
18 %
n = 22
24 %
14 %
n = 22
13 %
5 %
n = 22
mecillinam MEC
not for this site
0 %
0 %
n = 22
trimethoprim TMP
not for this site
0 %
0 %
n = 22
nitrofurantoin NIT
not for this site
0 %
0 %
n = 22

Most likely organisms for this profile

Staphylococcus aureus
45 %
Escherichia coli
14 %
Pseudomonas aeruginosa
14 %
Enterococcus faecalis
9 %
Proteus mirabilis
8 %
Citrobacter freundii
6 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.