Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-02-23
Based on 108 first isolates · ICU · Skin / wound infection · 2024-02-25 → 2025-02-23
Intensive care unit
Per-organism detail: ICU wound resistance view →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
meropenem 54 % (44 %–63 %)
Best two-drug combination: vancomycin + meropenem covers 99 % (95 %–100 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Staphylococcus aureus (34 %), Enterococcus faecalis (11 %), Pseudomonas aeruginosa (1 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Pseudomonas aeruginosa reserve
54 %
80 %
n = 5
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
50 %
60 %
n = 5
45 %
80 %
n = 5
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
45 %
20 %
n = 5
ceftriaxone CRO
trend · Escherichia coli
38 %
80 %
n = 5
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
33 %
0 %
n = 5
32 %
60 %
n = 5
32 %
60 %
n = 5
12 %
0 %
n = 5
mecillinam MEC
not for this site
0 %
0 %
n = 5
trimethoprim TMP
not for this site
0 %
0 %
n = 5
nitrofurantoin NIT
not for this site
0 %
0 %
n = 5

Most likely organisms for this profile

Staphylococcus aureus
34 %
Pseudomonas aeruginosa
15 %
Escherichia coli
15 %
Proteus mirabilis
11 %
Enterococcus faecalis
11 %
Klebsiella pneumoniae
7 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.