Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-03-16
Based on 504 first isolates · MED-A · Febrile UTI / pyelonephritis · 2024-03-17 → 2025-03-16
Internal medicine A
Per-organism detail: MED-A urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
piperacillin-tazobactam 81 % (78 %–84 %)
Keep for severe or hospital-onset infections.
Not covered: Enterococcus faecalis (9 %), Escherichia coli (4 %), Staphylococcus aureus (4 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
86 %
90 %
n = 29
nitrofurantoin NIT
trend · Escherichia coli not for this site
83 %
86 %
n = 29
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
81 %
86 %
n = 29
ciprofloxacin CIP
trend · Escherichia coli
79 %
90 %
n = 29
mecillinam MEC
trend · Escherichia coli not for this site
79 %
86 %
n = 29
ceftriaxone CRO
trend · Escherichia coli
79 %
83 %
n = 29
73 %
83 %
n = 29
trimethoprim TMP
trend · Escherichia coli not for this site
72 %
86 %
n = 29
47 %
55 %
n = 29
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
10 %
n = 29
5 %
3 %
n = 29
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
4 %
3 %
n = 29

Most likely organisms for this profile

Escherichia coli
58 %
Klebsiella pneumoniae
9 %
Enterococcus faecalis
9 %
Proteus mirabilis
7 %
Pseudomonas aeruginosa
5 %
Klebsiella oxytoca
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.