Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-04-13
Based on 641 first isolates · URO · Cystitis (lower UTI) · 2024-04-14 → 2025-04-13
Urology
Per-organism detail: URO urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 84 % (81 %–86 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (6 %), Klebsiella pneumoniae (5 %), Pseudomonas aeruginosa (4 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
84 %
88 %
n = 43
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
84 %
91 %
n = 43
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
80 %
86 %
n = 43
mecillinam MEC
trend · Escherichia coli lower UTI only
76 %
86 %
n = 43
ceftriaxone CRO
trend · Escherichia coli
76 %
79 %
n = 43
ciprofloxacin CIP
trend · Escherichia coli
76 %
72 %
n = 43
trimethoprim TMP
trend · Escherichia coli lower UTI only
71 %
72 %
n = 43
69 %
72 %
n = 43
47 %
51 %
n = 43
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
12 %
12 %
n = 43
4 %
0 %
n = 43
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
0 %
n = 43

Most likely organisms for this profile

Escherichia coli
57 %
Klebsiella pneumoniae
11 %
Enterococcus faecalis
9 %
Proteus mirabilis
6 %
Pseudomonas aeruginosa
4 %
Staphylococcus aureus
3 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.