Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-04-13
Based on 114 first isolates · ICU · Skin / wound infection · 2024-04-14 → 2025-04-13
Intensive care unit
Per-organism detail: ICU wound resistance view →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 50 % (41 %–59 %)
Best two-drug combination: vancomycin + meropenem covers 98 % (94 %–100 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Escherichia coli (14 %), Pseudomonas aeruginosa (14 %), Proteus mirabilis (9 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
50 %
91 %
n = 11
meropenem MEM
trend · Escherichia coli reserve
48 %
9 %
n = 11
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
46 %
9 %
n = 11
ciprofloxacin CIP
trend · Escherichia coli
41 %
9 %
n = 11
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
36 %
55 %
n = 11
ceftriaxone CRO
trend · Escherichia coli
34 %
9 %
n = 11
30 %
36 %
n = 11
29 %
9 %
n = 11
11 %
0 %
n = 11
mecillinam MEC
not for this site
0 %
0 %
n = 11
trimethoprim TMP
not for this site
0 %
0 %
n = 11
nitrofurantoin NIT
not for this site
0 %
0 %
n = 11

Most likely organisms for this profile

Staphylococcus aureus
39 %
Escherichia coli
14 %
Pseudomonas aeruginosa
14 %
Enterococcus faecalis
11 %
Proteus mirabilis
9 %
Klebsiella pneumoniae
7 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.