Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-04-20
Based on 117 first isolates · ICU · Skin / wound infection · 2024-04-21 → 2025-04-20
Intensive care unit
Per-organism detail: ICU wound resistance view →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 51 % (42 %–60 %)
Best two-drug combination: vancomycin + meropenem covers 98 % (94 %–100 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Pseudomonas aeruginosa (15 %), Escherichia coli (14 %), Proteus mirabilis (9 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
51 %
81 %
n = 16
meropenem MEM
trend · Pseudomonas aeruginosa reserve
47 %
19 %
n = 16
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
45 %
19 %
n = 16
41 %
19 %
n = 16
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
38 %
63 %
n = 16
ceftriaxone CRO
trend · Escherichia coli
32 %
13 %
n = 16
29 %
25 %
n = 16
27 %
13 %
n = 16
12 %
6 %
n = 16
mecillinam MEC
not for this site
0 %
0 %
n = 16
trimethoprim TMP
not for this site
0 %
0 %
n = 16
nitrofurantoin NIT
not for this site
0 %
0 %
n = 16

Most likely organisms for this profile

Staphylococcus aureus
40 %
Pseudomonas aeruginosa
15 %
Escherichia coli
14 %
Enterococcus faecalis
11 %
Proteus mirabilis
9 %
Citrobacter freundii
6 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.