Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-05-04
Based on 528 first isolates · MED-A · Febrile UTI / pyelonephritis · 2024-05-05 → 2025-05-04
Internal medicine A
Per-organism detail: MED-A urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
meropenem 85 % (82 %–88 %)
Carbapenem: reserve for ESBL / critically ill patients.
Not covered: Enterococcus faecalis (10 %), Staphylococcus aureus (4 %), Staphylococcus saprophyticus (1 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
85 %
80 %
n = 40
nitrofurantoin NIT
trend · Escherichia coli not for this site
82 %
88 %
n = 40
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
70 %
n = 40
ciprofloxacin CIP
trend · Escherichia coli
78 %
75 %
n = 40
mecillinam MEC
trend · Escherichia coli not for this site
78 %
75 %
n = 40
ceftriaxone CRO
trend · Escherichia coli
77 %
73 %
n = 40
72 %
70 %
n = 40
trimethoprim TMP
trend · Escherichia coli not for this site
71 %
75 %
n = 40
47 %
50 %
n = 40
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
15 %
n = 40
5 %
3 %
n = 40
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
4 %
3 %
n = 40

Most likely organisms for this profile

Escherichia coli
56 %
Klebsiella pneumoniae
10 %
Enterococcus faecalis
10 %
Proteus mirabilis
8 %
Pseudomonas aeruginosa
5 %
Klebsiella oxytoca
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.