Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-05-25
Based on 406 first isolates · MED-B · Cystitis (lower UTI) · 2024-05-26 → 2025-05-25
Internal medicine B
Per-organism detail: MED-B urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 84 % (80 %–87 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (7 %), Klebsiella pneumoniae (4 %), Pseudomonas aeruginosa (4 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
85 %
83 %
n = 36
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
84 %
78 %
n = 36
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
78 %
72 %
n = 36
mecillinam MEC
trend · Escherichia coli lower UTI only
78 %
75 %
n = 36
ciprofloxacin CIP
trend · Escherichia coli
78 %
75 %
n = 36
ceftriaxone CRO
trend · Escherichia coli
77 %
69 %
n = 36
74 %
67 %
n = 36
trimethoprim TMP
trend · Escherichia coli lower UTI only
69 %
72 %
n = 36
50 %
44 %
n = 36
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
14 %
17 %
n = 36
3 %
3 %
n = 36
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
11 %
n = 36

Most likely organisms for this profile

Escherichia coli
57 %
Enterococcus faecalis
11 %
Klebsiella pneumoniae
10 %
Proteus mirabilis
7 %
Pseudomonas aeruginosa
4 %
Klebsiella oxytoca
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.