Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-06-01
Based on 438 first isolates · GER · Cystitis (lower UTI) · 2024-06-02 → 2025-06-01
Geriatrics
Per-organism detail: GER urine resistance view → ⚠ 1 active alert in GER: they are taken into account below. View alerts →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 83 % (79 %–86 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (7 %), Klebsiella pneumoniae (5 %), Pseudomonas aeruginosa (4 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
⚠ CPE case in the ward: carbapenem resistance possible
84 %
84 %
n = 49
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
83 %
90 %
n = 49
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
80 %
80 %
n = 49
mecillinam MEC
trend · Escherichia coli lower UTI only
76 %
80 %
n = 49
ceftriaxone CRO
trend · Escherichia coli
76 %
71 %
n = 49
ciprofloxacin CIP
trend · Escherichia coli
76 %
73 %
n = 49
71 %
67 %
n = 49
trimethoprim TMP
trend · Escherichia coli lower UTI only
69 %
61 %
n = 49
48 %
39 %
n = 49
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
8 %
n = 49
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
5 %
2 %
n = 49
4 %
4 %
n = 49

Most likely organisms for this profile

Escherichia coli
57 %
Klebsiella pneumoniae
10 %
Enterococcus faecalis
8 %
Proteus mirabilis
7 %
Staphylococcus aureus
5 %
Pseudomonas aeruginosa
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.