Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-06-15
Based on 644 first isolates · URO · Cystitis (lower UTI) · 2024-06-16 → 2025-06-15
Urology
Per-organism detail: URO urine resistance view → ⚠ 3 active alerts in URO: they are taken into account below. View alerts →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 83 % (80 %–86 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (6 %), Klebsiella pneumoniae (6 %), Pseudomonas aeruginosa (5 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
84 %
81 %
n = 58
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
83 %
86 %
n = 58
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
78 %
n = 58
mecillinam MEC
trend · Escherichia coli lower UTI only
76 %
72 %
n = 58
ciprofloxacin CIP
trend · Escherichia coli
⚠ Escherichia coli: 34 % resistant in the last 4 weeks (baseline 10 %)
75 %
60 %
n = 58
ceftriaxone CRO
trend · Escherichia coli
⚠ Active ESBL cluster (11 cases)
⚠ Escherichia coli: 31 % resistant in the last 4 weeks (baseline 4 %)
74 %
59 %
n = 58
trimethoprim TMP
trend · Escherichia coli lower UTI only
68 %
59 %
n = 58
⚠ Active ESBL cluster (11 cases)
67 %
57 %
n = 58
⚠ Active ESBL cluster (11 cases)
48 %
47 %
n = 58
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
17 %
n = 58
⚠ Active ESBL cluster (11 cases)
4 %
3 %
n = 58
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
5 %
n = 58

Most likely organisms for this profile

Escherichia coli
57 %
Klebsiella pneumoniae
11 %
Enterococcus faecalis
10 %
Proteus mirabilis
6 %
Pseudomonas aeruginosa
5 %
Staphylococcus saprophyticus
3 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.