Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-06-22
Based on 644 first isolates · URO · Cystitis (lower UTI) · 2024-06-23 → 2025-06-22
Urology
Per-organism detail: URO urine resistance view → ⚠ 5 active alerts in URO: they are taken into account below. View alerts →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 84 % (81 %–86 %)
No tissue or blood levels: cystitis only.
Not covered: Klebsiella pneumoniae (6 %), Proteus mirabilis (5 %), Pseudomonas aeruginosa (5 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
84 %
83 %
n = 60
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
84 %
92 %
n = 60
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
80 %
n = 60
mecillinam MEC
trend · Escherichia coli lower UTI only
76 %
75 %
n = 60
ciprofloxacin CIP
trend · Escherichia coli
⚠ Escherichia coli: 49 % resistant in the last 4 weeks (baseline 10 %)
75 %
52 %
n = 60
ceftriaxone CRO
trend · Escherichia coli
⚠ Active ESBL cluster (17 cases)
⚠ Escherichia coli: 46 % resistant in the last 4 weeks (baseline 4 %)
73 %
53 %
n = 60
⚠ Active ESBL cluster (17 cases)
⚠ Escherichia coli: 46 % resistant in the last 4 weeks (baseline 13 %)
67 %
52 %
n = 60
trimethoprim TMP
trend · Escherichia coli lower UTI only
⚠ Escherichia coli: 51 % resistant in the last 4 weeks (baseline 20 %)
67 %
52 %
n = 60
⚠ Active ESBL cluster (17 cases)
48 %
30 %
n = 60
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
13 %
n = 60
⚠ Active ESBL cluster (17 cases)
4 %
2 %
n = 60
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
5 %
n = 60

Most likely organisms for this profile

Escherichia coli
58 %
Klebsiella pneumoniae
11 %
Enterococcus faecalis
10 %
Proteus mirabilis
5 %
Pseudomonas aeruginosa
5 %
Staphylococcus saprophyticus
3 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.