Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 1246 first isolates · PHC-N · Febrile UTI / pyelonephritis · 2024-06-30 → 2025-06-29
Health centre North
Per-organism detail: PHC-N urine resistance view → ⚠ 1 active alert in PHC-N: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
piperacillin-tazobactam 79 % (77 %–81 %)
Best two-drug combination: vancomycin + piperacillin-tazobactam covers 93 % (92 %–95 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Enterococcus faecalis (11 %), Staphylococcus aureus (3 %), Staphylococcus saprophyticus (2 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
nitrofurantoin NIT
trend · Escherichia coli not for this site
83 %
78 %
n = 118
meropenem MEM
trend · Escherichia coli reserve
⚠ CPE case in the ward: carbapenem resistance possible
83 %
92 %
n = 118
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
88 %
n = 118
ciprofloxacin CIP
trend · Escherichia coli
77 %
88 %
n = 118
mecillinam MEC
trend · Escherichia coli not for this site
76 %
87 %
n = 118
ceftriaxone CRO
trend · Escherichia coli
76 %
85 %
n = 118
trimethoprim TMP
trend · Escherichia coli not for this site
72 %
82 %
n = 118
71 %
80 %
n = 118
51 %
52 %
n = 118
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
14 %
6 %
n = 118
4 %
5 %
n = 118
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
1 %
n = 118

Most likely organisms for this profile

Escherichia coli
51 %
Klebsiella pneumoniae
13 %
Enterococcus faecalis
11 %
Proteus mirabilis
8 %
Pseudomonas aeruginosa
5 %
Citrobacter freundii
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.