Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 660 first isolates · URO · Febrile UTI / pyelonephritis · 2024-06-30 → 2025-06-29
Urology
Per-organism detail: URO urine resistance view → ⚠ 5 active alerts in URO: they are taken into account below. View alerts →
Narrowest option reaching 80 % coverage, no active warning
meropenem 84 % (81 %–87 %)
Carbapenem: reserve for ESBL / critically ill patients.
Not covered: Enterococcus faecalis (10 %), Staphylococcus aureus (3 %), Staphylococcus saprophyticus (3 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
meropenem MEM
trend · Escherichia coli reserve
84 %
90 %
n = 69
nitrofurantoin NIT
trend · Escherichia coli not for this site
84 %
91 %
n = 69
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
80 %
87 %
n = 69
mecillinam MEC
trend · Escherichia coli not for this site
77 %
81 %
n = 69
ciprofloxacin CIP
trend · Escherichia coli
⚠ Escherichia coli: 52 % resistant in the last 4 weeks (baseline 10 %)
74 %
54 %
n = 69
ceftriaxone CRO
trend · Escherichia coli
⚠ Active ESBL cluster (22 cases)
⚠ Escherichia coli: 50 % resistant in the last 4 weeks (baseline 5 %)
73 %
55 %
n = 69
trimethoprim TMP
trend · Escherichia coli not for this site
⚠ Escherichia coli: 50 % resistant in the last 4 weeks (baseline 21 %)
67 %
55 %
n = 69
⚠ Active ESBL cluster (22 cases)
⚠ Escherichia coli: 55 % resistant in the last 4 weeks (baseline 13 %)
66 %
49 %
n = 69
⚠ Active ESBL cluster (22 cases)
47 %
25 %
n = 69
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
7 %
n = 69
⚠ Active ESBL cluster (22 cases)
4 %
3 %
n = 69
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
6 %
n = 69

Most likely organisms for this profile

Escherichia coli
58 %
Klebsiella pneumoniae
12 %
Enterococcus faecalis
10 %
Proteus mirabilis
5 %
Pseudomonas aeruginosa
4 %
Staphylococcus aureus
3 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.