Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 1257 first isolates · PHC-S · Febrile UTI / pyelonephritis · 2024-08-18 → 2025-08-17
Health centre South
Per-organism detail: PHC-S urine resistance view → ⚠ 1 active alert in PHC-S: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
piperacillin-tazobactam 77 % (75 %–80 %)
Best two-drug combination: vancomycin + piperacillin-tazobactam covers 93 % (91 %–94 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Enterococcus faecalis (12 %), Staphylococcus aureus (4 %), Staphylococcus saprophyticus (3 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
nitrofurantoin NIT
trend · Escherichia coli not for this site
82 %
82 %
n = 133
meropenem MEM
trend · Escherichia coli reserve
⚠ CPE case in the ward: carbapenem resistance possible
81 %
83 %
n = 133
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
77 %
79 %
n = 133
ciprofloxacin CIP
trend · Escherichia coli
75 %
76 %
n = 133
mecillinam MEC
trend · Escherichia coli not for this site
74 %
77 %
n = 133
ceftriaxone CRO
trend · Escherichia coli
74 %
78 %
n = 133
trimethoprim TMP
trend · Escherichia coli not for this site
71 %
66 %
n = 133
69 %
73 %
n = 133
51 %
53 %
n = 133
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
16 %
13 %
n = 133
4 %
4 %
n = 133
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
4 %
2 %
n = 133

Most likely organisms for this profile

Escherichia coli
48 %
Klebsiella pneumoniae
14 %
Enterococcus faecalis
12 %
Proteus mirabilis
8 %
Pseudomonas aeruginosa
5 %
Staphylococcus aureus
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.