Empirical therapy advisor
Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.
Based on 1085 first isolates · ED · Febrile UTI / pyelonephritis · 2024-09-29 → 2025-09-28
Emergency departmentNo single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
piperacillin-tazobactam 80 % (77 %–82 %)
Best two-drug combination: vancomycin + piperacillin-tazobactam covers 94 % (92 %–95 %)
Take cultures before treatment; consider a combination and discuss with infectious
diseases if the patient is severely ill.
Not covered: Enterococcus faecalis (10 %), Staphylococcus aureus (3 %), Escherichia coli (2 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
⚠ CPE case in the ward: carbapenem resistance possible
84 %
82 %
n = 90
Most likely organisms for this profile
Escherichia coli
56 %
Enterococcus faecalis
10 %
Klebsiella pneumoniae
10 %
Proteus mirabilis
6 %
Pseudomonas aeruginosa
6 %
Klebsiella oxytoca
4 %
Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.