Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

More options · any onset · target 80 % · 2025-11-16
Based on 457 first isolates · GER · Cystitis (lower UTI) · 2024-11-17 → 2025-11-16
Geriatrics
Per-organism detail: GER urine resistance view →
Narrowest option reaching 80 % coverage, no active warning
nitrofurantoin 84 % (81 %–87 %)
No tissue or blood levels: cystitis only.
Not covered: Proteus mirabilis (8 %), Klebsiella pneumoniae (4 %), Pseudomonas aeruginosa (4 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
nitrofurantoin NIT
trend · Escherichia coli lower UTI only
84 %
90 %
n = 39
meropenem MEM
trend · Escherichia coli reserve
84 %
77 %
n = 39
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
80 %
74 %
n = 39
mecillinam MEC
trend · Escherichia coli lower UTI only
77 %
72 %
n = 39
ceftriaxone CRO
trend · Escherichia coli
77 %
74 %
n = 39
ciprofloxacin CIP
trend · Escherichia coli
76 %
67 %
n = 39
72 %
72 %
n = 39
trimethoprim TMP
trend · Escherichia coli lower UTI only
68 %
56 %
n = 39
51 %
64 %
n = 39
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
13 %
18 %
n = 39
4 %
3 %
n = 39
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
2 %
0 %
n = 39

Most likely organisms for this profile

Escherichia coli
57 %
Enterococcus faecalis
11 %
Klebsiella pneumoniae
9 %
Proteus mirabilis
8 %
Pseudomonas aeruginosa
4 %
Citrobacter freundii
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.