Empirical therapy advisor
Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.
Based on 137 first isolates · ICU · Skin / wound infection · 2025-03-30 → 2026-03-29
Intensive care unitNo single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 58 % (49 %–66 %)
Best two-drug combination: ciprofloxacin + vancomycin covers 93 % (88 %–97 %)
Take cultures before treatment; consider a combination and discuss with infectious
diseases if the patient is severely ill.
Not covered: Escherichia coli (12 %), Pseudomonas aeruginosa (12 %), Proteus mirabilis (7 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
⚠ Staphylococcus aureus: 65 % resistant in the last 4 weeks (baseline 6 %)
42 %
33 %
n = 15
⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
41 %
13 %
n = 15
⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
40 %
13 %
n = 15
ceftriaxone CRO
trend · Escherichia coli ⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
29 %
13 %
n = 15
cefuroxime CXM
trend · Escherichia coli ⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
28 %
13 %
n = 15
ampicillin AMP
trend · Escherichia coli ⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
20 %
7 %
n = 15
ceftazidime CAZ
trend · Pseudomonas aeruginosa ⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
10 %
0 %
n = 15
mecillinam MEC
not for this site⚠ Active MRSA cluster (13 cases): β-lactams do not cover MRSA
0 %
0 %
n = 15
trimethoprim TMP
not for this site0 %
0 %
n = 15
nitrofurantoin NIT
not for this site0 %
0 %
n = 15
Most likely organisms for this profile
Staphylococcus aureus
49 %
Escherichia coli
12 %
Pseudomonas aeruginosa
12 %
Enterococcus faecalis
9 %
Proteus mirabilis
7 %
Klebsiella pneumoniae
6 %
Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.