Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 572 first isolates · SURG · Skin / wound infection · 2025-05-11 → 2026-05-10
Surgery
Per-organism detail: SURG wound resistance view → ⚠ 1 active alert in SURG: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 54 % (50 %–58 %)
Best two-drug combination: ciprofloxacin + vancomycin covers 95 % (93 %–97 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Pseudomonas aeruginosa (14 %), Escherichia coli (12 %), Proteus mirabilis (9 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
54 %
48 %
n = 48
meropenem MEM
trend · Pseudomonas aeruginosa reserve
⚠ CPE case in the ward: carbapenem resistance possible
45 %
50 %
n = 48
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
42 %
40 %
n = 48
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
41 %
50 %
n = 48
41 %
48 %
n = 48
ceftriaxone CRO
trend · Escherichia coli
29 %
38 %
n = 48
27 %
33 %
n = 48
21 %
25 %
n = 48
12 %
13 %
n = 48
mecillinam MEC
not for this site
0 %
0 %
n = 48
trimethoprim TMP
not for this site
0 %
0 %
n = 48
nitrofurantoin NIT
not for this site
0 %
0 %
n = 48

Most likely organisms for this profile

Staphylococcus aureus
44 %
Pseudomonas aeruginosa
14 %
Escherichia coli
12 %
Enterococcus faecalis
10 %
Proteus mirabilis
9 %
Citrobacter freundii
6 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.