Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 135 first isolates · GER · Skin / wound infection · 2025-09-14 → 2026-09-13
Geriatrics
Per-organism detail: GER wound resistance view → ⚠ 1 active alert in GER: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
clindamycin 44 % (36 %–53 %)
Best two-drug combination: clindamycin + meropenem covers 83 % (76 %–88 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Enterococcus faecalis (16 %), Pseudomonas aeruginosa (14 %), Proteus mirabilis (10 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
⚠ VRE case in the ward
61 %
54 %
n = 13
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
44 %
23 %
n = 13
meropenem MEM
trend · Pseudomonas aeruginosa reserve
39 %
38 %
n = 13
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
35 %
23 %
n = 13
32 %
23 %
n = 13
25 %
38 %
n = 13
24 %
8 %
n = 13
22 %
8 %
n = 13
13 %
31 %
n = 13
mecillinam MEC
not for this site
0 %
0 %
n = 13
trimethoprim TMP
not for this site
0 %
0 %
n = 13
nitrofurantoin NIT
not for this site
0 %
0 %
n = 13

Most likely organisms for this profile

Staphylococcus aureus
46 %
Enterococcus faecalis
16 %
Pseudomonas aeruginosa
14 %
Proteus mirabilis
10 %
Escherichia coli
8 %
Klebsiella pneumoniae
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.