Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 137 first isolates · GER · Skin / wound infection · 2025-09-21 → 2026-09-20
Geriatrics
Per-organism detail: GER wound resistance view → ⚠ 1 active alert in GER: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
clindamycin 44 % (36 %–52 %)
Best two-drug combination: clindamycin + meropenem covers 84 % (77 %–89 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Enterococcus faecalis (15 %), Pseudomonas aeruginosa (15 %), Proteus mirabilis (9 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
⚠ VRE case in the ward
59 %
40 %
n = 15
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
44 %
27 %
n = 15
meropenem MEM
trend · Pseudomonas aeruginosa reserve
40 %
53 %
n = 15
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
36 %
33 %
n = 15
34 %
40 %
n = 15
25 %
13 %
n = 15
24 %
20 %
n = 15
23 %
13 %
n = 15
13 %
33 %
n = 15
mecillinam MEC
not for this site
0 %
0 %
n = 15
trimethoprim TMP
not for this site
0 %
0 %
n = 15
nitrofurantoin NIT
not for this site
0 %
0 %
n = 15

Most likely organisms for this profile

Staphylococcus aureus
45 %
Enterococcus faecalis
15 %
Pseudomonas aeruginosa
15 %
Proteus mirabilis
9 %
Escherichia coli
8 %
Citrobacter freundii
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.