Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 476 first isolates · MED-A · Febrile UTI / pyelonephritis · 2025-09-28 → 2026-09-27
Internal medicine A
Per-organism detail: MED-A urine resistance view → ⚠ 1 active alert in MED-A: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
piperacillin-tazobactam 79 % (75 %–82 %)
Best two-drug combination: vancomycin + piperacillin-tazobactam covers 93 % (90 %–95 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Enterococcus faecalis (11 %), Staphylococcus aureus (3 %), Staphylococcus saprophyticus (3 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
nitrofurantoin NIT
trend · Escherichia coli not for this site
84 %
84 %
n = 31
meropenem MEM
trend · Escherichia coli reserve
⚠ CPE case in the ward: carbapenem resistance possible
83 %
81 %
n = 31
piperacillin-tazobactam TZP
trend · Escherichia coli broad spectrum
79 %
81 %
n = 31
ciprofloxacin CIP
trend · Escherichia coli
77 %
81 %
n = 31
ceftriaxone CRO
trend · Escherichia coli
76 %
84 %
n = 31
mecillinam MEC
trend · Escherichia coli not for this site
76 %
84 %
n = 31
72 %
81 %
n = 31
trimethoprim TMP
trend · Escherichia coli not for this site
68 %
74 %
n = 31
50 %
52 %
n = 31
vancomycin VAN
trend · Enterococcus faecalis Gram-positive only
14 %
16 %
n = 31
3 %
0 %
n = 31
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
3 %
3 %
n = 31

Most likely organisms for this profile

Escherichia coli
55 %
Klebsiella pneumoniae
12 %
Enterococcus faecalis
11 %
Proteus mirabilis
6 %
Citrobacter freundii
4 %
Pseudomonas aeruginosa
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.