Empirical therapy advisor

Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.

Patient

Based on 138 first isolates · GER · Skin / wound infection · 2025-09-28 → 2026-09-27
Geriatrics
Per-organism detail: GER wound resistance view → ⚠ 1 active alert in GER: they are taken into account below. View alerts →
No single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
clindamycin 44 % (36 %–53 %)
Best two-drug combination: clindamycin + meropenem covers 85 % (78 %–90 %)
Take cultures before treatment; consider a combination and discuss with infectious diseases if the patient is severely ill.
Not covered: Pseudomonas aeruginosa (14 %), Enterococcus faecalis (14 %), Proteus mirabilis (10 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
vancomycin VAN
trend · Staphylococcus aureus Gram-positive only
⚠ VRE case in the ward
59 %
47 %
n = 19
clindamycin CLI
trend · Staphylococcus aureus Gram-positive only
44 %
37 %
n = 19
meropenem MEM
trend · Pseudomonas aeruginosa reserve
41 %
47 %
n = 19
piperacillin-tazobactam TZP
trend · Pseudomonas aeruginosa broad spectrum
36 %
32 %
n = 19
34 %
37 %
n = 19
25 %
16 %
n = 19
23 %
16 %
n = 19
23 %
16 %
n = 19
13 %
26 %
n = 19
mecillinam MEC
not for this site
0 %
0 %
n = 19
trimethoprim TMP
not for this site
0 %
0 %
n = 19
nitrofurantoin NIT
not for this site
0 %
0 %
n = 19

Most likely organisms for this profile

Staphylococcus aureus
46 %
Pseudomonas aeruginosa
14 %
Enterococcus faecalis
14 %
Proteus mirabilis
10 %
Escherichia coli
8 %
Citrobacter freundii
4 %

Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.

AEI · Tyks Laboratoriot × Mylab · JunctionX Turku. Synteettinen aineisto; EARS-Net-luvut: ECDC.