Empirical therapy advisor
Before culture results are back: how likely is each antibiotic to cover the pathogen of a patient like this one, in this ward, given the last 12 months of results and today's alerts.
Based on 132 first isolates · ICU · Skin / wound infection · 2025-04-13 → 2026-04-12
Intensive care unitNo single agent reaches 80 % coverage for this profile. Highest coverage without active warning:
vancomycin 55 % (47 %–64 %)
Best two-drug combination: ciprofloxacin + vancomycin covers 93 % (88 %–96 %)
Take cultures before treatment; consider a combination and discuss with infectious
diseases if the patient is severely ill.
Not covered: Pseudomonas aeruginosa (14 %), Escherichia coli (12 %), Proteus mirabilis (8 %)
AntibioticCoverage, 12 months (95 % CI)12 mo4 wk
⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
43 %
27 %
n = 11
⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
42 %
27 %
n = 11
⚠ Staphylococcus aureus: 64 % resistant in the last 4 weeks (baseline 12 %)
41 %
27 %
n = 11
ceftriaxone CRO
trend · Escherichia coli ⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
30 %
18 %
n = 11
cefuroxime CXM
trend · Escherichia coli ⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
29 %
18 %
n = 11
ampicillin AMP
trend · Escherichia coli ⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
19 %
9 %
n = 11
ceftazidime CAZ
trend · Pseudomonas aeruginosa ⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
11 %
0 %
n = 11
mecillinam MEC
not for this site⚠ Active MRSA cluster (7 cases): β-lactams do not cover MRSA
0 %
0 %
n = 11
trimethoprim TMP
not for this site0 %
0 %
n = 11
nitrofurantoin NIT
not for this site0 %
0 %
n = 11
Most likely organisms for this profile
Staphylococcus aureus
48 %
Pseudomonas aeruginosa
14 %
Escherichia coli
12 %
Enterococcus faecalis
8 %
Proteus mirabilis
8 %
Klebsiella pneumoniae
6 %
Decision support only: coverage is the share of first isolates from similar patients that were susceptible (an organism not tested for a drug counts as not covered). It does not replace local treatment guidelines, allergy and severity assessment, or clinical judgement. The black tick on each bar is the coverage target; the bracket is the 95 % confidence interval.